Hepatectomy versus systemic therapy for liver-limited BRAF V600E-mutated colorectal liver metastases: multicentre retrospective study.

Georgios Antonios MargonisJaeyun Jane WangThomas BoernerRoberto MorettoStefan BuettnerNikolaos AndreatosJohan GagnièreDoris WagnerInger Marie LøesFrancesca BergamoFilippo PietrantonioMario ScartozziAndrea SpallanzaniBruno VincenziEfstathios AntoniouEmmanouil PikoulisAndrea Sartore-BianchiGeorgios StasinosKazunari SasakiTimothy M PawlikArmando OrlandiNicoletta PellaFabian FitschekKlaus KaczirekAurélien DupréIoannis PoziosKatharina BeyerPeter KornpratFederico N AucejoRichard BurkhartMatthew J WeissPer Eystein LønningGeorge PoultsidesChiara CremoliniMartin E KreisMichael D'Angelica

Published in: The British journal of surgery (2024)

BRAF V600E mutation should not be considered a contraindication to surgery for patients with resectable, liver-only CRLMs.

Keyphrases

liver metastases
wild type
minimally invasive
metastatic colorectal cancer
coronary artery bypass
clinical trial
study protocol
cross sectional
coronary artery disease
acute coronary syndrome
atrial fibrillation