Characteristics of the esophageal microbiome in patients with achalasia and its changes before and after peroral endoscopic myotomy: A pilot study.
Chia-Chu YehChieh-Chang ChenChien-Chuan ChenMing-Lun HanJia-Feng WuHsiu-Po WangMing-Shiang WuPing-Huei TsengPublished in: Journal of gastroenterology and hepatology (2023)
The altered esophageal microenvironment in achalasia leads to dysbiosis with a high abundance of genus Lactobacillus. Increased Neisseria and decreased Lactobacillus were observed after POEM. The long-term effect of microbial changes warrants further study.