Axicabtagene ciloleucel compared to standard of care in Swedish patients with large B-cell lymphoma: a cost-effectiveness analysis of the ZUMA-7 trial.
Anne Sofie Ledgaard LoftagerAnne DanøOskar EklundSachin VadgamaViktor Hedlof KanjeEmma MunkPublished in: Journal of medical economics (2023)
2L treatment with axi-cel in transplant-intended DLBCL patients with early r/r after completing 1L chemoimmunotherapy was cost-effective compared to SOC in a Swedish setting. Administering axi-cel in 2L is cost-effective as it enhances the possibility of curing more patients, resulting in not just a survival advantage, but also a reduction in the burden on quality of life and cost of subsequent therapy. This will be advantageous to both patients and society.
Keyphrases
- end stage renal disease
- chronic kidney disease
- ejection fraction
- newly diagnosed
- healthcare
- clinical trial
- diffuse large b cell lymphoma
- palliative care
- randomized controlled trial
- stem cells
- study protocol
- bone marrow
- patient reported outcomes
- risk factors
- pain management
- phase iii
- patient reported
- open label
- cell therapy
- health insurance
- free survival