von Willebrand factor increases in experimental cerebral malaria but is not essential for late-stage pathogenesis in mice.
Sirima KraisinKimberly MartinodLinda DesenderInge PareynSebastien VerhenneHans DeckmynKaren VanhoorelbekePhilippe E Van den SteenSimon F De MeyerPublished in: Journal of thrombosis and haemostasis : JTH (2020)
Our study suggests that increased VWF concentration is a hallmark of ECM. However, VWF does not have a major influence in modulating late-stage ECM pathogenesis.