Karen Vanhoorelbeke (K Vanhoorelbeke)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 28

Top Topics

Trypanosoma Cruzi

Disease Activity

Acute Respiratory Distress Syndrome

Top Venues

Journal of thrombosis and haemostasis : JTH

This page only lists publications with an associated author ORCID identifier.

Publications

Nithya Prasannan, Bertina Dragunaite, Maryam Subhan, Mari Thomas, Rens de Groot, Deepak Singh, Karen Vanhoorelbeke, Marie Scully
Peak ADAMTS13 activity to assess ADAMTS13 conformation and risk of relapse in immune-mediated thrombotic thrombocytopenic purpura. Blood 143 (25) (2024)
Nithya Prasannan, Bertina Dragunaite, Maryam Owais Subhan, Mari Thomas, Rens de Groot, Deepak Singh, Karen Vanhoorelbeke, Marie Scully
Peak ADAMTS13 activity to assess ADAMTS13 conformation and risk of relapse in immune-mediated Thrombotic Thrombocytopenic Purpura. Blood (2024)
Nithya Prasannan, Bertina Dragunaite, Maryam Owais Subhan, Mari Thomas, Rens de Groot, Deepak Singh, Karen Vanhoorelbeke, Marie Scully
Peak ADAMTS13 activity to assess ADAMTS13 conformation and risk of relapse in immune-mediated Thrombotic Thrombocytopenic Purpura. Blood (2024)
Jolien Breukers, Karen Ven, Caroline Struyfs, Louanne Ampofo, Iene Rutten, Maya Imbrechts, Francesca Pollet, Julie Van Lent, Winnie Kerstens, Sam Noppen, Dominique Schols, Paul De Munter, Hendrik-Jan Thibaut, Karen Vanhoorelbeke, Dragana Spasic, Paul J Declerck, Bruno P A Cammue, Nick Geukens, Karin Thevissen, Jeroen Lammertyn
FLUIDOT: A Modular Microfluidic Platform for Single-Cell Study and Retrieval, with Applications in Drug Tolerance Screening and Antibody Mining. Small methods (2023)
Jolien Breukers, Karen Ven, Caroline Struyfs, Louanne Ampofo, Iene Rutten, Maya Imbrechts, Francesca Pollet, Julie Van Lent, Winnie Kerstens, Sam Noppen, Dominique Schols, Paul De Munter, Hendrik-Jan Thibaut, Karen Vanhoorelbeke, Dragana Spasic, Paul J Declerck, Bruno P A Cammue, Nick Geukens, Karin Thevissen, Jeroen Lammertyn
FLUIDOT: A Modular Microfluidic Platform for Single-Cell Study and Retrieval, with Applications in Drug Tolerance Screening and Antibody Mining. Small methods 7 (3) (2023)
Jolien Breukers, Karen Ven, Caroline Struyfs, Louanne Ampofo, Iene Rutten, Maya Imbrechts, Francesca Pollet, Julie Van Lent, Winnie Kerstens, Sam Noppen, Dominique Schols, Paul De Munter, Hendrik-Jan Thibaut, Karen Vanhoorelbeke, Dragana Spasic, Paul J Declerck, Bruno P A Cammue, Nick Geukens, Karin Thevissen, Jeroen Lammertyn
FLUIDOT: A Modular Microfluidic Platform for Single-Cell Study and Retrieval, with Applications in Drug Tolerance Screening and Antibody Mining. Small methods 7 (3) (2023)
Jolien Breukers, Karen Ven, Caroline Struyfs, Louanne Ampofo, Iene Rutten, Maya Imbrechts, Francesca Pollet, Julie Van Lent, Winnie Kerstens, Sam Noppen, Dominique Schols, Paul De Munter, Hendrik-Jan Thibaut, Karen Vanhoorelbeke, Dragana Spasic, Paul J Declerck, Bruno P A Cammue, Nick Geukens, Karin Thevissen, Jeroen Lammertyn
FLUIDOT: A Modular Microfluidic Platform for Single-Cell Study and Retrieval, with Applications in Drug Tolerance Screening and Antibody Mining. Small methods 7 (3) (2023)
Jolien Breukers, Karen Ven, Caroline Struyfs, Louanne Ampofo, Iene Rutten, Maya Imbrechts, Francesca Pollet, Julie Van Lent, Winnie Kerstens, Sam Noppen, Dominique Schols, Paul De Munter, Hendrik-Jan Thibaut, Karen Vanhoorelbeke, Dragana Spasic, Paul J Declerck, Bruno P A Cammue, Nick Geukens, Karin Thevissen, Jeroen Lammertyn
FLUIDOT: A Modular Microfluidic Platform for Single-Cell Study and Retrieval, with Applications in Drug Tolerance Screening and Antibody Mining. Small methods 7 (3) (2023)
Dr Tanja Falter, Heidi Rossmann, Laure de Waele, Charlotte Dekimpe, Charis von Auer, Nadine Mueller-Calleja, Friederike Häuser, Adriana Degreif, Dana Marandiuc, Xavier Messmer, Martin F Sprinzl, Karl J Lackner, Kerstin Jurk, Karen Vanhoorelbeke, Bernhard Lämmle
A novel von Willebrand factor multimer ratio as marker of disease activity in thrombotic thrombocytopenic purpura. Blood advances (2023)
Nicolas Béranger, Paul Coppo, Vassilis Tsatsaris, Pierre Boisseau, François Provôt, Yahsou Delmas, Pascale Poullin, Karen Vanhoorelbeke, Agnès Veyradier, Bérangère S Joly
Management and follow-up of pregnancy-onset thrombotic thrombocytopenic purpura: the French experience. Blood advances (2023)
Bojing Shao, Christopher Hoover, Huiping Shi, Yuji Kondo, Robert Hugh Lee, Junmei Chen, Xindi Shan, Jianhua Song, J Michael McDaniel, Meixiang Zhou, Samuel McGee, Karen Vanhoorelbeke, Wolfgang Bergmeier, José A López, James N George, Lijun Xia
Deletion of platelet CLEC-2 decreases GPIbα-mediated integrin αIIbβ3 activation and decreases thrombosis in TTP. Blood 139 (16) (2022)
Nuno A G Graça, Bérangère S Joly, Jan Voorberg, Karen Vanhoorelbeke, Nicolas Béranger, Agnès Veyradier, Paul Coppo
TTP: From empiricism for an enigmatic disease to targeted molecular therapies. British journal of haematology 197 (2) (2022)
Kazuya Sakai, Masanori Matsumoto, Laure de Waele, Charlotte Dekimpe, Eriko Nakamura, Masayuki Kubo, Claudia Tersteeg, Simon F De Meyer, Karen Vanhoorelbeke
ADAMTS13 conformation and immunoprofiles in Japanese patients with immune-mediated thrombotic thrombocytopenic purpura. Blood advances (2022)
Shannen J Deconinck, Christoph Nix, Svenja Barth, Eveline Bennek-Schöpping, Antoine Rauch, An-Sofie Schelpe, Elien Roose, Hendrik B Feys, Inge Pareyn, Aline Vandenbulcke, Joshua Muia, Christophe Vandenbriele, Sophie Susen, Bart Meyns, Claudia Tersteeg, Steven Jacobs, Simon F De Meyer, Karen Vanhoorelbeke
ADAMTS13 inhibition to treat acquired von Willebrand syndrome during mechanical circulatory support device implantation. Journal of thrombosis and haemostasis : JTH 20 (12) (2022)
Kadri Kangro, Elien Roose, Charlotte Dekimpe, Aline Vandenbulcke, Nuno A G Graça, Jan Voorberg, Mart Ustav, Andres Männik, Karen Vanhoorelbeke
Improvement of recombinant ADAMTS13 production through a more optimal signal peptide or an N-terminal fusion protein. Journal of thrombosis and haemostasis : JTH 20 (10) (2022)
Senna Staessens, Mouhamed Djahoum Moussa, Adeline Pierache, Antoine Rauch, Natacha Rousse, Eric Boulleaux, Alexandre Ung, Linda Desender, Bénédicte Pradines, André Vincentelli, Ida Chiara Guerrera, Julien Labreuche, Alain Duhamel, Eric Van Belle, Flavien Vincent, Annabelle Dupont, Karen Vanhoorelbeke, Delphine Corseaux, Simon F De Meyer, Sophie Susen
Thrombus formation during ECMO: Insights from a detailed histological analysis of thrombus composition. Journal of thrombosis and haemostasis : JTH 20 (9) (2022)
Laure de Waele, Alexandre Curie, Kadri Kangro, Edwige Tellier, Gilles Kaplanski, Andres Männik, Claudia Tersteeg, Bérangère S Joly, Paul Coppo, Agnès Veyradier, Simon F De Meyer, Elien Roose, Karen Vanhoorelbeke
Anti-cysteine/spacer antibodies that open ADAMTS13 are a common feature in iTTP. Blood advances 5 (21) (2021)
Sévérine de Bruijn, Marie-Berthe Maes, Laure de Waele, Karen Vanhoorelbeke, Alain Gadisseur
First report of a de novo iTTP episode associated with an mRNA-based anti-COVID-19 vaccination. Journal of thrombosis and haemostasis : JTH 19 (8) (2021)
Steven de Maat, Chantal C Clark, Arjan D Barendrecht, Simone Smits, Nadine D van Kleef, Hinde El Otmani, Manon Waning, Marc Vincent Adriaan van Moorsel, Michael Szardenings, Nicolas Delaroque, Kristof Vercruysse, Rolf T Urbanus, Silvie Sebastian, Peter J Lenting, Christoph Eugen Hagemeyer, Thomas Renne, Karen Vanhoorelbeke, Claudia Tersteeg, Coen Maas
Microlyse; a thrombolytic agent that targets VWF for clearance of microvascular thrombosis. Blood (2021)
Bogac Ercig, Nuno A G Graça, Kadri Kangro, Tom Arfman, Kanin Wichapong, Johana Hrdinová, Paul Kaijen, Floris P J van Alphen, Maartje van den Biggelaar, Karen Vanhoorelbeke, Agnès Veyradier, Paul Coppo, Chris P M Reutelingsperger, Gerry A F Nicolaes, Andres Männik, Jan Voorberg
N-glycan-mediated shielding of ADAMTS13 prevents binding of pathogenic autoantibodies in immune-mediated TTP. Blood 137 (19) (2021)
Derek J B Kleinveld, Derek D G Simons, Charlotte Dekimpe, Shannen J Deconinck, Pieter H Sloos, M Adrie W Maas, Jesper Kers, Joshua Muia, Karim Brohi, Jan Voorberg, Karen Vanhoorelbeke, Markus W Hollmann, Nicole P Juffermans, null null
Plasma and rhADAMTS13 reduce trauma-induced organ failure by restoring the ADAMTS13-VWF axis. Blood advances 5 (17) (2021)
Hyo Jung Kim, Yaoxian Xu, A Petri, Karen Vanhoorelbeke, James T B Crawley, Jonas Emsley
Crystal structure of ADAMTS13 CUB domains reveals their role in global latency. Science advances 7 (16) (2021)
Kadri Kangro, Elien Roose, Bérangère S Joly, György Sinkovits, Tanja Falter, Charis von Auer, Heidi Rossmann, Marienn Reti, Jan Voorberg, Zoltán Prohászka, Bernhard Lämmle, Paul Coppo, Agnès Veyradier, Simon F De Meyer, Andres Männik, Karen Vanhoorelbeke
Anti-ADAMTS13 autoantibody profiling in patients with immune-mediated thrombotic thrombocytopenic purpura. Blood advances 5 (17) (2021)
Sirima Kraisin, Kimberly Martinod, Linda Desender, Inge Pareyn, Sebastien Verhenne, Hans Deckmyn, Karen Vanhoorelbeke, Philippe E Van den Steen, Simon F De Meyer
von Willebrand factor increases in experimental cerebral malaria but is not essential for late-stage pathogenesis in mice. Journal of thrombosis and haemostasis : JTH 18 (9) (2020)
Joshua Muia, Jian Zhu, Suellen C Greco, Karen Vanhoorelbeke, Garima Gupta, Lisa A Westfield, J Evan Sadler
Phylogenetic and functional analysis of ADAMTS13 identifies highly conserved domains essential for allosteric regulation. Blood 133 (17) (2019)
Jian Zhu, Joshua Muia, Garima Gupta, Lisa A Westfield, Karen Vanhoorelbeke, Niraj H Tolia, J Evan Sadler
Exploring the "minimal" structure of a functional ADAMTS13 by mutagenesis and small-angle X-ray scattering. Blood 133 (17) (2019)
Sirima Kraisin, Sebastien Verhenne, Thao-Thy Pham, Kimberly Martinod, Claudia Tersteeg, Nele Vandeputte, Hans Deckmyn, Karen Vanhoorelbeke, Philippe E Van den Steen, Simon F De Meyer
von Willebrand factor in experimental malaria-associated acute respiratory distress syndrome. Journal of thrombosis and haemostasis : JTH 17 (8) (2019)
Claudia Tersteeg, Jan Roodt, Walter J Van Rensburg, Charlotte Dekimpe, Nele Vandeputte, Inge Pareyn, Aline Vandenbulcke, Barbara Plaimauer, Seb Lamprecht, Hans Deckmyn, José A Lopez, Simon F De Meyer, Karen Vanhoorelbeke
N-acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura. Blood 129 (8) (2016)