Up-Regulation of PARP1 Expression Significantly Correlated with Poor Survival in Mucosal Melanomas.

Piotr DonizyCheng-Lin WuJason MullMasakazu FujimotoAgata ChłopikYan PengSara C ShalinM Angelica SelimSusana PuigMaria-Teresa Fernandez-FiguerasChristopher R SheaWojciech BiernatJanusz RyśAndrzej MarszalekMai P Hoang

Published in: Cells (2020)

Increased expression of PARP1 is an independent negative prognostic marker in mucosal melanomas. The association between PARP1 and IDO1 and their combined adverse prognostic role raise the potential of combined therapy in mucosal melanoma.

Keyphrases

dna damage
poor prognosis
dna repair
ulcerative colitis
binding protein
skin cancer
climate change
electronic health record
adverse drug