Desorption ionization using through-hole alumina membrane offers higher reproducibility than 2,5-dihydroxybenzoic acid, a widely used matrix in Fourier transform ion cyclotron resonance mass spectrometry imaging analysis.
Md Mahmudul HasanFumihiro EtoMd Al MamunShumpei SatoAriful IslamA S M WaliullahDo Huu ChiYutaka TakahashiTomoaki KahyoYasuhide NaitoMasahiro KotaniTakayuki OhmuraMitsutoshi SetouPublished in: Rapid communications in mass spectrometry : RCM (2021)
Our results demonstrated that DIUTHAME-MS offers higher reproducibility for mass accuracies and intensities than MALDI-MS in both standard lipid and mouse brain tissue analyses. It can potentially be used instead of conventional MALDI-MS and mass spectrometry imaging analyses to achieve highly reproducible data for mass accuracy and intensity.
Keyphrases
- mass spectrometry
- high resolution
- gas chromatography
- liquid chromatography
- high performance liquid chromatography
- capillary electrophoresis
- tandem mass spectrometry
- electronic health record
- multiple sclerosis
- machine learning
- high intensity
- fatty acid
- ms ms
- energy transfer
- fluorescence imaging
- deep learning
- simultaneous determination
- perovskite solar cells