Hair glucocorticoid levels decrease after multimodal inpatient treatment and predict therapy outcome in burnout-related depressive disorders.

Roberto La MarcaMonika ScheiwillerMichael PfaffPearl La Marca-GhaemmaghamiHeinz Böker

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2024)

These results suggest that multimodal inpatient treatment of clinical burnout considerably reduced stress on both a psychological and biological level. In parallel, hair glucocorticoids appear to be sensitive biomarkers for the evaluation of treatment success and prediction. Examining both HCC and HCNC in intervention studies may provide clearer results than the usual examination of HCC alone.

Keyphrases

randomized controlled trial
mental health
palliative care
stem cells
pain management
physical activity
replacement therapy
bone marrow
sleep quality
drug induced