Brain angiogenic gene expression in fetuses with congenital heart disease.

O SánchezA Ruiz-RomeroC DomínguezQ FerrerI RiberaV Rodríguez-SuredaJ AlijotasS ArévaloE CarrerasL CaberoElisa Llurba

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2018)

An overall dysregulation of angiogenesis with a net balance towards an antiangiogenic environment was observed in the cerebral tissue of fetuses with CHD, suggesting that these fetuses may have an intrinsic angiogenic impairment that could contribute to impaired brain perfusion and abnormal neurological development later in life. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.

Keyphrases

multiple sclerosis
white matter
gestational age
gene expression
cerebral ischemia
resting state
subarachnoid hemorrhage
functional connectivity
dna methylation
preterm birth
randomized controlled trial
brain injury
systematic review
wound healing