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Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study.

Andjelija Zivanovic BujakChen-Fang WengMaria João SilvaMiriam M YeungLouisa L LoSarah FtouniCassandra LitchfieldYi-An KoKeilly KuykhovenCourtney Van GeelenSushma ChandrashekarMark A DawsonSherene LoiStephen Q WongSarah-Jane Dawson
Published in: PLoS medicine (2020)
In this study, we found prospective ctDNA testing to be a practical and feasible approach that can guide clinical trial enrolment and patient management in mBC.
Keyphrases
  • clinical trial
  • metastatic breast cancer
  • circulating tumor
  • health insurance
  • phase ii
  • open label
  • double blind
  • study protocol
  • palliative care
  • phase iii
  • single molecule
  • cell free
  • nucleic acid