Sarah-Jane Dawson

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 34

Top Venues

Nature cell biology

Nature communications

Nature medicine

Clinical cancer research : an official journal of the American Association for Cancer Research

Peter MacCallum Cancer Institute

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Peter MacCallum Cancer Institute Mar 01 2014

Australia

Medical Oncologist and Group Leader :: Division of Cancer Medicine and Research

Education History

University of Cambridge Jan 05 2007 - Jan 01 2011

United Kingdom

PHD :: Oncology

Publications

Lavinia Tan, Chris Brown, Antony Mersiades, Chee Khoon Lee, Thomas John, Steven Kao, Genni Newnham, Kenneth O'Byrne, Sagun Parakh, Victoria Bray, Kevin Jasas, Sonia Yip, Stephen Q Wong, Sarah Ftouni, Jerick Guinto, Sushma Chandrashekar, Stephen Clarke, Nick Pavlakis, Martin R Stockler, Sarah-Jane Dawson, Benjamin J Solomon
A Phase II trial of alternating osimertinib and gefitinib therapy in advanced EGFR-T790M positive non-small cell lung cancer: OSCILLATE. Nature communications 15 (1) (2024)
Sasanka Mithila Handunnetti, Mary Ann Anderson, Kate I Burbury, Phillip A Thompson, Glenda Burke, Mathias Bressel, Juliana Di Iulio, Rodney John Hicks, David Westerman, Stephen Lade, Christiane Pott, Rishu Agarwal, Rachel M Koldej, David S Ritchie, Martin Dreyling, Mark A Dawson, Sarah-Jane Dawson, John Francis Seymour, Andrew W Roberts, Constantine S Tam
Seven-year outcomes of venetoclax-ibrutinib therapy in mantle cell lymphoma: durable responses and treatment-free remissions. Blood 144 (8) (2024)
Lavinia Tan, Chris Brown, Antony Mersiades, Chee Khoon Lee, Thomas John, Steven Kao, Genni Newnham, Kenneth O'Byrne, Sagun Parakh, Victoria Bray, Kevin Jasas, Sonia Yip, Stephen Q Wong, Sarah Ftouni, Jerick Guinto, Sushma Chandrashekar, Stephen Clarke, Nick Pavlakis, Martin R Stockler, Sarah-Jane Dawson, Benjamin J Solomon
A Phase II trial of alternating osimertinib and gefitinib therapy in advanced EGFR-T790M positive non-small cell lung cancer: OSCILLATE. Nature communications 15 (1) (2024)
Lavinia Tan, Chris Brown, Antony Mersiades, Chee Khoon Lee, Thomas John, Steven Kao, Genni Newnham, Kenneth O'Byrne, Sagun Parakh, Victoria Bray, Kevin Jasas, Sonia Yip, Stephen Q Wong, Sarah Ftouni, Jerick Guinto, Sushma Chandrashekar, Stephen Clarke, Nick Pavlakis, Martin R Stockler, Sarah-Jane Dawson, Benjamin J Solomon
A Phase II trial of alternating osimertinib and gefitinib therapy in advanced EGFR-T790M positive non-small cell lung cancer: OSCILLATE. Nature communications 15 (1) (2024)
Lavinia Tan, Ben Tran, Jeanne Tie, Benjamin Markman, Sumi Ananda, Niall C Tebbutt, Michael Michael, Emma Link, Stephen Q Wong, Sushma Chandrashekar, Jerick Guinto, David S Ritchie, Rachel M Koldej, Benjamin J Solomon, Grant A McArthur, Rodney John Hicks, Peter Gibbs, Sarah-Jane Dawson, Jayesh Desai
A Phase Ib/II Trial of Combined BRAF and EGFR Inhibition in BRAF V600E Positive Metastatic Colorectal Cancer and Other Cancers: The EVICT (Erlotinib and Vemurafenib In Combination Trial) Study. Clinical cancer research : an official journal of the American Association for Cancer Research 29 (6) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Lavinia Tan, Ben Tran, Jeanne Tie, Benjamin Markman, Sumi Ananda, Niall C Tebbutt, Michael Michael, Emma Link, Stephen Q Wong, Sushma Chandrashekar, Jerick Guinto, David S Ritchie, Rachel M Koldej, Benjamin J Solomon, Grant A McArthur, Rodney John Hicks, Peter Gibbs, Sarah-Jane Dawson, Jayesh Desai
Phase Ib/II Trial of BRAF and EGFR inhibition in BRAFV600E metastatic colorectal cancer and other cancers: EVICT (Erlotinib and Vemurafenib In Combination Trial). Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Ymke van der Pol, Norbert Moldovan, Jip Ramaker, Sanne Bootsma, Kristiaan J Lenos, Louis Vermeulen, Shahneen Sandhu, Idris Bahce, D Michiel Pegtel, Stephen Q Wong, Sarah-Jane Dawson, Dineika Chandrananda, Florent Mouliere
The landscape of cell-free mitochondrial DNA in liquid biopsy for cancer detection. Genome biology 24 (1) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Lavinia Tan, Ben Tran, Jeanne Tie, Benjamin Markman, Sumi Ananda, Niall C Tebbutt, Michael Michael, Emma Link, Stephen Q Wong, Sushma Chandrashekar, Jerick Guinto, David S Ritchie, Rachel M Koldej, Benjamin J Solomon, Grant A McArthur, Rodney John Hicks, Peter Gibbs, Sarah-Jane Dawson, Jayesh Desai
A Phase Ib/II Trial of Combined BRAF and EGFR Inhibition in BRAF V600E Positive Metastatic Colorectal Cancer and Other Cancers: The EVICT (Erlotinib and Vemurafenib In Combination Trial) Study. Clinical cancer research : an official journal of the American Association for Cancer Research 29 (6) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kah Lok Chan, Charles C Bell, Omer Gilan, Yih-Chih Chan, Sarah Popp, Daniel J Gough, Melanie A Eckersley-Maslin, Sarah-Jane Dawson, Paul J Lehner, Kate D Sutherland, Patricia Ernst, Gerard M McGeehan, Enid Y N Lam, Marian L Burr, Mark A Dawson
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. Nature cell biology 25 (2) (2023)
Peter Savas, Louisa L Lo, Stephen J Luen, Elizabeth F Blackley, Jason Callahan, Kate Moodie, Courtney T van Geelen, Yi-An Ko, Chen-Fang Weng, Lironne Wein, Maria João Silva, Andjelija Zivanovic Bujak, Miriam M Yeung, Sarah Ftouni, Rodney John Hicks, Prudence A Francis, Chee Khoon Lee, Sarah-Jane Dawson, Sherene Loi
Alpelisib Monotherapy for PI3K-Altered, Pretreated Advanced Breast Cancer: A Phase II Study. Cancer discovery 12 (9) (2022)
Lorenzo Gerratana, Jean-Yves Pierga, James M Reuben, Andrew A Davis, Firas H Wehbe, Luc Dirix, Tanja Fehm, Franco Nolé, Rafael Gisbert-Criado, Dimitrios Mavroudis, Salvatore Grisanti, Jose A Garcia-Saenz, Justin Stebbing, Carlos Caldas, Paola Gazzaniga, Luis Manso, Rita Zamarchi, Marta Bonotto, Angela Fernandez de Lascoiti, Leticia De Mattos-Arruda, Michail Ignatiadis, Maria-Teresa Sandri, Daniele Generali, Carmine De Angelis, Sarah-Jane Dawson, Wolfgang Janni, Vicente Carañana, Sabine Riethdorf, Erich-Franz Solomayer, Fabio Puglisi, Mario Giuliano, Klaus Pantel, Francois-Clement Bidard, Massimo Cristofanilli
Modeling the Prognostic Impact of Circulating Tumor Cells Enumeration in Metastatic Breast Cancer for Clinical Trial Design Simulation. The oncologist 27 (7) (2022)
Ismael A Vergara, Christopher P Mintoff, Shahneen Sandhu, Lachlan McIntosh, Richard J Young, Stephen Q Wong, Andrew Colebatch, Daniel L Cameron, Julia Lai Kwon, Rory Wolfe, Angela Peng, Jason Ellul, Xuelin Dou, Clare Fedele, Samantha Boyle, Gisela Mir Arnau, Jeanette Raleigh, Athena Hatzimihalis, Pacman Szeto, Jennifer Mooi, Daniel S Widmer, Phil Fang Cheng, Valerie Amann, Reinhard Dummer, Nicholas K Hayward, James S Wilmott, Richard A Scolyer, Raymond J Cho, David Bowtell, Heather Thorne, Kathryn Alsop, Stephen Cordner, Noel Woodford, Jodie Leditschke, Patricia O'Brien, Sarah-Jane Dawson, Grant A McArthur, Graham J Mann, Mitchell P Levesque, Anthony T Papenfuss, Mark Shackleton
Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling. Nature communications 12 (1) (2021)
Nila J Dharan, Paul Yeh, Mark Bloch, Miriam M Yeung, David Baker, Jerick Guinto, Norman Roth, Sarah Ftouni, Katherine Ognenovska, Don Smith, Jennifer F Hoy, Ian J Woolley, Catherine Pell, David J Templeton, Neil Fraser, Nectarios Rose, Jolie Hutchinson, Kathy Petoumenos, Sarah-Jane Dawson, Mark N Polizzotto, Mark A Dawson, null null
HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults. Nature medicine 27 (6) (2021)
Sylvain Garciaz, Andrew A Guirguis, Sebastian Muller, Fiona C Brown, Yih-Chih Chan, Ali Motazedian, Caitlin L Rowe, James A Kuzich, Kah Lok Chan, Kevin Tran, Lorey Smith, Laura MacPherson, Brian J Liddicoat, Enid Y N Lam, Tatiana Cañeque, Marian L Burr, Veronique Litalien, Giovanna Pomilio, Mathilde Poplineau, Estelle Duprez, Sarah-Jane Dawson, Georg Ramm, Andrew Graham Cox, Kristin K Brown, David Ching Siang Huang, Andrew H Wei, Kate McArthur, Raphaël Rodriguez, Mark A Dawson
Pharmacological reduction of mitochondrial iron triggers a non-canonical BAX/BAK dependent cell death. Cancer discovery (2021)
Enrique Zozaya-Valdés, Stephen Q Wong, Jeanette Raleigh, Athena Hatzimihalis, Sarah Ftouni, Anthony T Papenfuss, Shahneen Sandhu, Mark A Dawson, Sarah-Jane Dawson
Detection of cell-free microbial DNA using a contaminant-controlled analysis framework. Genome biology 22 (1) (2021)
Katie A Fennell, Dane Vassiliadis, Enid Y N Lam, Luciano G Martelotto, Jesse J Balic, Sebastian Hollizeck, Tom S Weber, Timothy Semple, Qing Wang, Denise C Miles, Laura MacPherson, Yih-Chih Chan, Andrew A Guirguis, Lev M Kats, Emily S Wong, Sarah-Jane Dawson, Shalin H Naik, Mark A Dawson
Non-genetic determinants of malignant clonal fitness at single-cell resolution. Nature (2021)
Stephen-John Sammut, Mireia Crispin-Ortuzar, Suet-Feung Chin, Elena Provenzano, Helen A Bardwell, Wenxin Ma, Wei Cope, Ali Dariush, Sarah-Jane Dawson, Jean E Abraham, Janet Dunn, Louise Hiller, Jeremy Thomas, David A Cameron, John M S Bartlett, Larry Hayward, Paul David Peter Pharoah, Florian Markowetz, Oscar M Rueda, Helena M Earl, Carlos Caldas
Multi-omic machine learning predictor of breast cancer therapy response. Nature (2021)
Maarten J IJzerman, Jasper de Boer, Arun Azad, Koen Degeling, Joel Geoghegan, Chelsee Hewitt, Frédéric Hollande, Belinda Lee, Yat Ho To, Richard W Tothill, Gavin Wright, Jeanne Tie, Sarah-Jane Dawson
Towards Routine Implementation of Liquid Biopsies in Cancer Management: It Is Always Too Early, until Suddenly It Is Too Late. Diagnostics (Basel, Switzerland) 11 (1) (2021)
Andjelija Zivanovic Bujak, Chen-Fang Weng, Maria João Silva, Miriam M Yeung, Louisa L Lo, Sarah Ftouni, Cassandra Litchfield, Yi-An Ko, Keilly Kuykhoven, Courtney Van Geelen, Sushma Chandrashekar, Mark A Dawson, Sherene Loi, Stephen Q Wong, Sarah-Jane Dawson
Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study. PLoS medicine 17 (10) (2020)
Stephen Q Wong, Sarah-Jane Dawson
Combining liquid biopsies and PET-CT for early cancer detection. Nature medicine 26 (7) (2020)
Omer Gilan, Inmaculada Rioja, Kathy Knezevic, Matthew J Bell, Miriam M Yeung, Nicola R Harker, Enid Y N Lam, Chun-Wa Chung, Paul Bamborough, Massimo Petretich, Marjeta Urh, Stephen J Atkinson, Anna K Bassil, Emma J Roberts, Dane Vassiliadis, Marian L Burr, Alex G S Preston, Christopher R Wellaway, Thilo Werner, James R Gray, Anne-Marie Michon, Thomas Gobbetti, Vinod Kumar, Peter E Soden, Andrea Haynes, Johanna Vappiani, David F Tough, Simon J Taylor, Sarah-Jane Dawson, Marcus Bantscheff, Matthew Lindon, Gerard Drewes, Emmanuel H Demont, Danette L Daniels, Paola Grandi, Rabinder K Prinjha, Mark A Dawson
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation. Science (New York, N.Y.) 368 (6489) (2020)
Charles C Bell, Katie A Fennell, Yih-Chih Chan, Florian Rambow, Miriam M Yeung, Dane Vassiliadis, Luis Lara, Paul Yeh, Luciano G Martelotto, Aljosja Rogiers, Brandon E Kremer, Olena Barbash, Helai P Mohammad, Timothy M Johanson, Marian L Burr, Arindam Dhar, Natalie Karpinich, Lu-Yi Tian, Dean S Tyler, Laura MacPherson, Junwei Shi, Nathan Pinnawala, Chun Yew Fong, Anthony T Papenfuss, Sean M Grimmond, Sarah-Jane Dawson, Rhys S Allan, Ryan G Kruger, Christopher R Vakoc, David L Goode, Shalin H Naik, Omer Gilan, Enid Y N Lam, Jean-Christophe Marine, Rabinder K Prinjha, Mark A Dawson
Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia. Nature communications 10 (1) (2019)
Rishu Agarwal, Yih-Chih Chan, Constantine S Tam, Tane Hunter, Dane Vassiliadis, Charis E Teh, Rachel Thijssen, Paul Yeh, Stephen Q Wong, Sarah Ftouni, Enid Y N Lam, Mary Ann Anderson, Christiane Pott, Omer Gilan, Charles C Bell, Kathy Knezevic, Piers Blombery, Kathleen Rayeroux, Adrian Zordan, Jason Li, David C S Huang, Meaghan Wall, John F Seymour, Daniel H D Gray, Andrew W Roberts, Mark A Dawson, Sarah-Jane Dawson
Dynamic molecular monitoring reveals that SWI-SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma. Nature medicine 25 (1) (2018)
Dean S Tyler, Johanna Vappiani, Tatiana Cañeque, Enid Y N Lam, Aoife Ward, Omer Gilan, Yih-Chih Chan, Antje Hienzsch, Anna Rutkowska-Klute, Thilo Werner, Anne J Wagner, Dave Lugo, Richard Gregory, Cesar Ramirez Molina, Neil Garton, Christopher R Wellaway, Susan Jackson, Laura MacPherson, Margarida Figueiredo, Sabine Stolzenburg, Charles C Bell, Colin House, Sarah-Jane Dawson, Edwin D Hawkins, Gerard Drewes, Rabinder K Prinjha, Raphaël Rodriguez, Paola Grandi, Mark A Dawson
Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science (New York, N.Y.) 356 (6345) (2017)
Paul Yeh, Michael Dickinson, Sarah Ftouni, Tane Hunter, Devbarna Sinha, Stephen Q Wong, Rishu Agarwal, Ravikiran Vedururu, Kenneth Doig, Chun Yew Fong, Piers Blombery, David Westerman, Mark A Dawson, Sarah-Jane Dawson
Molecular disease monitoring using circulating tumor DNA in myelodysplastic syndromes. Blood 129 (12) (2017)
Peter Savas, Zhi Ling Teo, Christophe M Lefèvre, Christoffer Flensburg, Franco Caramia, Kathryn Alsop, Mariam Mansour, Prudence A Francis, Heather A Thorne, Maria Joao Silva, Nnennaya Kanu, Michelle Dietzen, Andrew Rowan, Maik Kschischo, Stephen B Fox, David D Bowtell, Sarah-Jane Dawson, Terence P Speed, Charles Swanton, Sherene Loi
The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE". PLoS medicine 13 (12) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Sarah-Jane Dawson