Implementation of a centralized HPV-based cervical cancer screening programme in Tuscany: First round results and comparison with the foregoing Pap-based screening programme.
Francesca CarozziElena BurroniMassimo ConfortiniGiampaolo PompeoSimonetta BisanziFilippo CellaiIrene PaganiniPaola MantelliniAnna IossaLisa LelliCarmelina Di PierroMarzia MatucciStefania CannistrĂ Roberta RosatiAlessandra MongiaCarmen Beatriz VisioliGiuseppe GoriniCristina Saninull The Tuscany Hpv-Based Screening Working GroupPublished in: Journal of medical screening (2022)
HPV-based is more effective in detecting high-grade precancerous and cancerous lesions than Pap-based screening and is characterized by an "anticipatory effect" in the detection of CIN2+ lesions. The transition from Pap-based to HPV-based screening programme should include increased resources dedicated to colposcopy services. Centralization in a laboratory with long experience in this field promotes efficiency of the screening process.