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Investigating the effect of poly-l-lactic acid nanoparticles carrying hypericin on the flow-biased diffusive motion of HeLa cell organelles.

Rozhin PenjweiniSarah DevilleOmid Haji MaghsoudiKristof NotelaersAnitha EthirajanMarcel Ameloot
Published in: The Journal of pharmacy and pharmacology (2017)
Image correlation and cross-correlation spectroscopy are most appropriate to unravel the motion of the PLLA nanocarrier and to demonstrate that the rate of the directed motion of organelles is influenced by their interaction with the nanocarriers. Not all PLLA-hypericin NPs are associated with organelles.
Keyphrases
  • lactic acid
  • drug delivery
  • high speed
  • single cell
  • deep learning
  • high resolution
  • single molecule
  • drug release
  • machine learning
  • cell cycle arrest
  • walled carbon nanotubes