Optimum Differentiation of Frontotemporal Lobar Degeneration from Alzheimer Disease Achieved with Cross-Sectional Tau Positron Emission Tomography.
Keith Anthony JosephsNirubol TosakulwongRodolfo G GattoStephen D WeigandFarwa AliHugo BothaJonathan Graff-RadfordMary M MachuldaRodolfo SavicaChristopher G SchwarzMatthew L SenjemBradley F BoeveKejal KantarciDavid T JonesVijay K RamananJulie A FieldsRoss R ReichardGourisankar GhoshRonald C PetersenClifford R JackVal J LoweJennifer L WhitwellPublished in: Annals of neurology (2022)
There are cross-sectional and longitudinal differences in flortaucipir uptake between FTLD and high and low ADNC. However, optimum differentiation between FTLD and ADNC was achieved with baseline uptake rather than longitudinal rates. ANN NEUROL 2022;92:1016-1029.