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Laser-Synthesized SERS Substrates as Sensors toward Therapeutic Drug Monitoring.

Matteo TommasiniChiara Giuseppina ZanchiAndrea LucottiAlessandro BombelliNicolò S VillaMarina CasazzaEmilio CiusaniUgo de GraziaMarco SantoroEnza FazioFortunato NeriSebastiano TrussoPaolo Maria Ossi
Published in: Nanomaterials (Basel, Switzerland) (2019)
The synthesis by pulsed laser ablation and the characterization of both the surface nanostructure and the optical properties of noble metal nanoparticle-based substrates used in Surface Enhanced Raman Spectroscopy are discussed with reference to application in the detection of anti-epileptic drugs. Results on two representative drugs, namely Carbamazepine and Perampanel, are critically addressed.
Keyphrases
  • raman spectroscopy
  • high speed
  • label free
  • cross sectional
  • loop mediated isothermal amplification
  • drug induced
  • radiofrequency ablation
  • sensitive detection
  • low cost
  • real time pcr
  • iron oxide