Impact of cascade screening for catecholaminergic polymorphic ventricular tachycardia type 1.

Keiko ShimamotoSeiko OhnoKoichi KatoKoichiro TakayamaKeiko SonodaMegumi FukuyamaTakeru MakiyamaSatomi OkamuraKoko AsakuraNoriaki ImanishiYoshiaki KatoHeima SakaguchiTsukasa KamakuraMitsuru WadaKenichiro YamagataKohei IshibashiYuko InoueKoji MiyamotoSatoshi NagaseKengo F KusanoMinoru HorieTakeshi Aiba

Published in: Heart (British Cardiac Society) (2022)

variants showed an earlier onset of symptoms than those with assured familial inheritance. Cascade screening may enable early diagnosis, risk stratification and prophylactic therapeutic intervention to prevent sudden cardiac death of probands and potential genotype-positive family members.

Keyphrases

randomized controlled trial
copy number
mitochondrial dna
early onset
sleep quality
physical activity
climate change