Down-regulation of increased TRAF6 expression in the peripheral mononuclear cells of patients with primary Sjögren's syndrome by an EBV-EBER1-specific synthetic single-stranded complementary DNA molecule.
Sándor SipkaErika ZilahiGábor PappJi-Qing ChenAndrea NagyKatalin HegyiJózsef KónyaMargit ZeherPublished in: International journal of rheumatic diseases (2017)
These findings give a further evidence of the linkage between EBV and pSS, furthermore, they show the possible role of EBV-EBER1 in the induction of increased TRAF6 expression in the peripheral B cells of Sjögren's patients.
Keyphrases
- epstein barr virus
- poor prognosis
- diffuse large b cell lymphoma
- binding protein
- end stage renal disease
- ejection fraction
- newly diagnosed
- induced apoptosis
- cell cycle arrest
- peritoneal dialysis
- chemotherapy induced
- single molecule
- circulating tumor
- case report
- long non coding rna
- cell death
- nucleic acid
- patient reported