Evaluation of the sensitivity and specificity of a novel line immunoassay for the detection of criteria and non-criteria antiphospholipid antibodies in comparison to established ELISAs.
Markus A ThalerAndreas BietenbeckUdo SteigerwaldThomas BüttnerPeter SchierackEdelgard Lindhoff-LastDirk RoggenbuckPeter B LuppaPublished in: PloS one (2019)
The LIA constitutes a valuable diagnostic tool for aPL profiling. It offers increased sensitivity for the detection of aPL against anionic phospholipids. In contrast, ELISAs exhibit strengths for the sensitive detection of aPL against neutral phospholipids.