Drug Repurposing in Crohn's Disease Using Danish Real-World Data.
Saeed ShakibfarKristine Højgaard AllinTine JessMaria Antonietta BarbieriVera BattiniEva SimoncicJulien KirchgesnerTrond UlvenMaurizio SessaPublished in: Pragmatic and observational research (2024)
This study focuses on repurposing existing drugs to prevent surgery related to intestinal fibrosis in CD patients, using Danish EHRs and advanced statistical methods. The findings offer valuable insights into potential treatments for this condition, addressing a critical unmet medical need. Further research and clinical trials are warranted to validate the effectiveness of these repurposed drugs in preventing surgery related to intestinal fibrosis in CD patients.
Keyphrases
- end stage renal disease
- clinical trial
- ejection fraction
- newly diagnosed
- minimally invasive
- randomized controlled trial
- peritoneal dialysis
- systematic review
- healthcare
- emergency department
- coronary artery disease
- atrial fibrillation
- electronic health record
- deep learning
- surgical site infection
- risk assessment
- liver fibrosis