Disease burden and pain in obese cancer patients with chemotherapy-induced peripheral neuropathy.
Emily Cox-MartinLisa H TrahanMatthew G CoxPatrick M DoughertyEmily A LaiDiane M NovyPublished in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2017)
Cancer survivors with CIPN and co-occurring obesity may be more at risk for decreased quality of life through increased symptom severity and pain compared to non-obese survivors. This paper identified risk factors, including obesity, age, and months since treatment, that can be clinically identified for monitoring distress in CIPN patients. Future research should focus on the longitudinal relationship between obesity and CIPN, and robust interventions to address the multifaceted issues faced by cancer survivors.
Keyphrases
- chemotherapy induced
- weight loss
- metabolic syndrome
- insulin resistance
- type diabetes
- risk factors
- bariatric surgery
- young adults
- adipose tissue
- chronic pain
- high fat diet induced
- end stage renal disease
- weight gain
- pain management
- ejection fraction
- chronic kidney disease
- neuropathic pain
- newly diagnosed
- peritoneal dialysis
- obese patients
- prognostic factors
- patient reported outcomes
- cross sectional
- childhood cancer
- spinal cord
- spinal cord injury
- postoperative pain