Accelerated Lung Function Decline and Mucus-Microbe Evolution in Chronic Obstructive Pulmonary Disease.
Oliver W MeldrumGavin C DonaldsonJayanth Kumar NarayanaFransiskus Xaverius IvanTavleen K JaggiMicheál Mac AogáinLydia J FinneyJames P AllinsonJadwiga A WedzichaSanjay Haresh ChotirmallPublished in: American journal of respiratory and critical care medicine (2024)
Mucus-microbiome associations evolve over time with accelerated lung function decline, symptom progression and exacerbations affording fresh therapeutic opportunities for early intervention.