In Vitro Chondrogenic Differentiation of Human Adipose-Derived Stem Cells by Diacerein.

Ali Honarpardaz Morteza Daliri JoupariSajjad Tavakkoli

Published in: Iranian journal of pharmaceutical research : IJPR (2023)

We observed that diacerein alone could initiate and enhance chondrogenesis, and it can be used as a differentiation factor for stem cells to chondrocyte besides its ability to inhibit IL-1β. Knowing the actual function of diacerein, it could be a good candidate for the treatment of osteoarthritis.

Keyphrases

stem cells
endothelial cells
mesenchymal stem cells
rheumatoid arthritis
induced pluripotent stem cells
pluripotent stem cells
knee osteoarthritis
cell therapy
combination therapy
replacement therapy