Effect of allopurinol in addition to hypothermia treatment in neonates for hypoxic-ischemic brain injury on neurocognitive outcome (ALBINO): study protocol of a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III).

Christian A MaiwaldKim V AnninkMario RüdigerManon J N L BendersFrank van BelKarel AllegaertGunnar NaulaersDirk BasslerKatrin Klebermaß-SchrehofMaximo VentoHercilia GuimarãesTom StirisLuigi CattarossiMarjo MetsärantaSampsa VanhataloJan MazelaTuuli MetsvahtYannique JacobsAxel R Franznull null

Published in: BMC pediatrics (2019)

NCT03162653, www.ClinicalTrials.gov , May 22, 2017.

Keyphrases

phase iii
placebo controlled
brain injury
double blind
study protocol
subarachnoid hemorrhage
phase ii
clinical trial
open label
phase ii study
cerebral ischemia
randomized controlled trial
cardiac arrest
squamous cell carcinoma
bipolar disorder
low birth weight
rectal cancer