Hypothalamic CREB Regulates the Expression of Pomc-Processing Enzyme Pcsk2.

Ariane Maria Zanesco Natália Ferreira Mendes Daiane Fátima EngelRodrigo S GasparDavi Sidarta-OliveiraJose DonatoLicio A Velloso

Published in: Cells (2022)

This study provides the first evidence for the involvement of CREB in the abnormal regulation of the hypothalamic Pomc endopeptidase system in experimental obesity.

Keyphrases

poor prognosis
metabolic syndrome
insulin resistance
type diabetes
weight loss
weight gain
binding protein