Evoked potentials as biomarkers of hereditary spastic paraplegias: A case-control study.

Samanta Ferraresi BrighentePaul VicuñaAna Luiza Rodrigues LouzadaGabriela Marchisio GiordaniHelena FussigerMarco Antonnio Rocha Dos SantosDiana Maria Cubillos-ArcilaPablo Brea WincklerJonas Alex Morales Saute

Published in: PloS one (2021)

Motor and somatosensory evoked potentials can adequately differentiate HSP individuals from controls. MEP were severely affected in HSP subjects and SSEP-LL latencies were prolonged, with longer latencies being related to more severe disease. Future longitudinal studies should address if SSEP is a sensitive disease progression biomarker for HSP.

Keyphrases

heat shock protein
heat shock
heat stress
early onset
current status
cerebral palsy
cross sectional
case control
drug induced