Postoperative bleeding complications in patients with hemophilia undergoing major orthopedic surgery: A prospective multicenter observational study.

Brendan KleiboerMarcus A LayerLorraine A CafuirAdam CukerMiguel EscobarM Elaine EysterEric KrautAndrew D LeavittSteven R LentzDoris QuonMargaret V RagniDianne ThornhillMichael WangNigel S KeyTyler W Buckner
Published in: Journal of thrombosis and haemostasis : JTH (2022)
The bleeding risk remains substantial after THA and TKA in PWH, despite factor replacement. Use of antifibrinolytic medications is associated with decreased risk.