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The effects of rutin on cisplatin induced oxidative retinal and optic nerve injury: an experimental study.

Nurdan Gamze TaşlıTurgay UcakYücel KarakurtFerda Keskin CimenAsli Ozbek BilginNezahat KurtHalis Suleyman
Published in: Cutaneous and ocular toxicology (2018)
Concomitant rutin administration may prevent the detrimental effects of cisplatin on lipid peroxidation, oxidative stress and inflammation markers and may also avert the histopathological damage on retina and optic nerve. Further studies are warranted to determine the effects of cisplatin and rutin on eye.
Keyphrases
  • optic nerve
  • oxidative stress
  • optical coherence tomography
  • dna damage
  • diabetic rats
  • ischemia reperfusion injury
  • induced apoptosis
  • fatty acid
  • case control
  • signaling pathway