Surgical clipping or endovascular coiling for unruptured intracranial aneurysms: a pragmatic randomised trial.

Tim E DarsautJ Max FindlayJean RaymondMarc KotowskiDaniel RoyAlain WeillMichel W BojanowskiChiraz ChaalalaDaniela IancuHoward LesiukJohn SinclairFelix ScholtesDidier MartinMichael M ChowCian J O'KellyJohn H WongKen ButcherAllan J FoxAdam S ArthurFrancois GuilbertLu TianMiguel ChagnonSuzanne NoletGuylaine GevryJean Raymond

Published in: Journal of neurology, neurosurgery, and psychiatry (2017)

Surgical clipping or endovascular coiling of UIAs did not show differences in morbidity at 1 year. Trial continuation and additional randomised evidence will be necessary to establish the supposed superior efficacy of clipping.

Keyphrases

study protocol
internal carotid artery
open label
clinical trial
randomized controlled trial
phase iii
phase ii
middle cerebral artery
double blind
aortic dissection
placebo controlled