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Dairy Product Intake and Risk of Type 2 Diabetes in EPIC-InterAct: A Mendelian Randomization Study.

Linda E T VissersIvonne SluijsYvonne T van der SchouwNita G ForouhiFumiaki ImamuraStephen BurgessAurelio BarricarteHeiner BoeingCatalina BonetMaria-Dolores ChirlaqueGuy FagherazziPaul W FranksHeinz FreislingMarc J GunterJ Ramón QuirósDaniel B IbsenRudolf KaaksTimothy KeyKay-Tee KhawTilman KühnOlatz MokoroaPeter M NilssonKim OvervadValeria PalaDomenico PalliSalvatore PanicoCarlotta SacerdoteAnnemieke M W SpijkermanAnne TjonnelandRosario TuminoMiguel Rodríguez-BarrancoOlov RolandssonElio RiboliStephen J SharpClaudia LangenbergNicholas J Wareham
Published in: Diabetes care (2019)
rs4988235 was associated with milk intake but not with intake of other dairy products. This MR study does not suggest that milk intake is associated with diabetes, which is consistent with previous observational and genetic associations. LP may be associated with intake of other foods as well, but owing to the modest associations, we consider it unlikely that this caused the observed null result.
Keyphrases
  • type diabetes
  • weight gain
  • cardiovascular disease
  • glycemic control
  • magnetic resonance
  • gene expression
  • genome wide
  • dna methylation
  • metabolic syndrome
  • cross sectional