The In Vitro Immunomodulatory Effects of Gold Nanocomplex on THP-1-Derived Macrophages.

Duaa A AbuarqoubNouf N MahmoudRand ZazaRana Abu-DahabEnam A KhalilDima A Sabbah

Published in: Journal of immunology research (2022)

We can conclude that our nanocomplex is a potent effector that prevents tumoral progression by activating three main immunological strategies: switching the surface expression profile of the activated macrophages into a proinflammatory M1-like phenotype, downregulating the expression of proinflammatory cytokines, and upregulating the expression level of anti-inflammatory cytokines.

Keyphrases

poor prognosis
binding protein
signaling pathway
dendritic cells
long non coding rna
regulatory t cells
silver nanoparticles