Safety, tolerability, pharmacokinetics, and antitumour activity of oleclumab in Japanese patients with advanced solid malignancies: a phase I, open-label study.
Shunsuke KondoSatoru IwasaTakafumi KoyamaTomoko FujitaKo SugibayashiKosho MurayamaNoboru YamamotoPublished in: International journal of clinical oncology (2022)
Oleclumab was well tolerated in adult Japanese patients with advanced solid malignancies and no unexpected safety concerns were raised; oleclumab exposure increased with dose. Future studies on combination therapy with other agents are warranted.