In Vivo Study on the Effects of Xiaoaiping on the Stemness of Hepatocellular Carcinoma Cells.

Jing ZhanLiang-Liang ShiYan WangBai Wei Sheng-Li Yang

Published in: Evidence-based complementary and alternative medicine : eCAM (2019)

Xiaoaiping significantly inhibited the growth of HCC xenograft in nude mice. These antitumor effects may be mediated by modulating the expression of multiple stemness markers and totipotency factors and inhibition of the Hippo, Wnt, and Hedgehog signaling pathways.

Keyphrases

stem cells
signaling pathway
epithelial mesenchymal transition
poor prognosis
cell proliferation
high fat diet induced
oxidative stress
adipose tissue
endoplasmic reticulum stress
wild type