Higher Levels of Tumour-Infiltrating Lymphocytes (TILs) are Associated with a Better Prognosis, While CDK5 Plays a Different Role Between Nonmetastatic and Metastatic Colonic Carcinoma.

Qinghua WangRuihua YinXiaoxiao ChenBin HuBingjing JiangWanfen TangXia ZhangXiayun JinMingliang YingJianfei Fu

Published in: Cancer control : journal of the Moffitt Cancer Center (2023)

High expression of CDK5 indicates a good prognosis in nonmetastatic colon cancer, while it is the opposite in metastatic colon cancer, and the expression of CDK5 is unrelated to TILs. Patients with TIL-H have a better prognosis, with a proper cut-off value of 20% for colon cancer.

Keyphrases

cell cycle
poor prognosis
small cell lung cancer
squamous cell carcinoma
binding protein
peripheral blood
long non coding rna