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New approach for estimating risk of miscarriage after chorionic villus sampling.

María Del Mar GilF S MolinaM Rodríguez-FernándezJ L DelgadoM P CarrilloJacques C JaniW PlasenciaV StratievaN MaízP CarreteroA LismondeP ChaveevaJ BurgosB SantacruzJ ZamoraC De Paco Matallana
Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2020)
The risk of miscarriage in women undergoing CVS is about 1% higher than that in women who do not have CVS, although this excess risk is not solely attributed to the invasive procedure but, to some extent, to the demographic and pregnancy characteristics of the patients. After accounting for these risk factors and confining the analysis to low-risk pregnancies, CVS seems to increase the risk of miscarriage by about three times above the patient's background risk. Although this is a substantial increase in relative terms, in pregnancies without risk factors for miscarriage, the risk of miscarriage after CVS remains low and similar to, or slightly higher than, that in the general population. Copyright © 2020 ISUOG. Published by John Wiley & Sons Ltd.
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