Efficacy and safety of colchicine for the treatment of osteoarthritis: a systematic review and meta-analysis of intervention trials.

Ambrish SinghPablo Molina-GarciaSalman HussainAlok PaulSiddharth Kumar DasYing-Ying LeungCatherine L HillDebashish DandaJonathan SamuelsBenny Antony

Published in: Clinical rheumatology (2022)

Current evidence does not suggest a benefit of colchicine in reducing pain and improving physical function in the overall cohort of hand/knee OA patients. Future trials should focus on the subgroups of OA patients with local or systemic inflammation and/or mineralization who might benefit from colchicine.

Keyphrases

knee osteoarthritis
end stage renal disease
randomized controlled trial
ejection fraction
chronic kidney disease
newly diagnosed
chronic pain
rheumatoid arthritis
total knee arthroplasty
peritoneal dialysis
prognostic factors
current status
neuropathic pain
spinal cord
combination therapy
patient reported