Human milk oligosaccharide supplementation in irritable bowel syndrome patients: A parallel, randomized, double-blind, placebo-controlled study.

Cristina IribarrenHans TörnblomImran Aziz Maria K Magnusson Johanna Sundin Louise K Vigsnaes Ingvild Dybdrodt AmundsenBruce McConnellDorthe SeitzbergLena Öhman Magnus Simrén

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)

The 10 g dose of 2'FL/LNnT induced an increase in the beneficial Bifidobacterium spp. without aggravating gastrointestinal symptoms in patients with IBS. This approach may be worthwhile to modulate gut microbiota of IBS patients toward a healthier profile.

Keyphrases

double blind
irritable bowel syndrome
end stage renal disease
human milk
newly diagnosed
chronic kidney disease
placebo controlled
clinical trial
prognostic factors
randomized controlled trial
patient reported outcomes
physical activity
oxidative stress
depressive symptoms
sleep quality
phase iii
patient reported