Effect of 3, 2-Drug Combinations of Antihypertensive Therapies on Blood Pressure Variability in Black African Patients: Secondary Analyses of the CREOLE Trial.
Dike B OjjiVictoria CorneliusGiles PartingtonVeronica FrancisShahiemah PandieWynand SmytheNicky HickmanFelix BarasaAlbertino DamascenoAnastase DzudieErika S W JonesProssie Merab IngabireCharles MondoOkechukwu OgahElijah OgolaMahmoud U SaniGabriel Lamkur ShedulGrace ShedulBrian RaynerKaren SliwaNeil R Poulternull nullPublished in: Hypertension (Dallas, Tex. : 1979) (2022)
Compared with CCB-containing combinations, ACE-inhibitor plus thiazide was associated with higher levels, generally significant, of ambulatory and within-clinic systolic and diastolic BPV. These results supplement the differential ambulatory blood pressure-lowering effects of these therapies in the CREOLE trial.
Keyphrases
- blood pressure
- hypertensive patients
- heart rate
- end stage renal disease
- study protocol
- clinical trial
- ejection fraction
- phase iii
- newly diagnosed
- chronic kidney disease
- phase ii
- primary care
- randomized controlled trial
- peritoneal dialysis
- left ventricular
- emergency department
- metabolic syndrome
- type diabetes
- open label
- insulin resistance
- electronic health record
- drug induced