Real-world effectiveness of the CoronaVac vaccine in a retrospective population-based cohort in four Colombian cities (2021-2022).
Carlos Alberto Reina-BolañosMaría Patricia Arbeláez-MontoyaHugo BrangoDelia OrtegaCatalina Tovar-AceroLiliana López-CarvajalDoracelly Hincapié-PalacioAna Maritza Agudelo-VaccaGermán Avila-RodriguezPaula A Avilés-VergaraIngrid Liliana Minotta-DíazDavid Arango-LondoñoGeraldine Quintero-MonaMelanie Sánchez-OrozcoLaura Daniela Espinoza-MacaPablo RoaJuan Carlos Alzate-ÁngelAnthony Garcés-HurtadoSebastián ReinaAlberto Concha-EastmanPublished in: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases (2024)
CoronaVac demonstrated effectiveness in preventing death and hospitalisation during the first year of follow-up, but its effectiveness in preventing infection was lower, decreasing rapidly after the first 4 months of follow-up. The effectiveness was higher among children aged between 3 and 12 years, and among adults aged ≥60 years. Booster doses did not improve effectiveness among those already vaccinated with CoronaVac.