Genetic susceptibility for major depressive disorder associates with trajectories of depressive symptoms across childhood and adolescence.

Alexandre A LussierMatthew HawrilenkoMin-Jung Wang Karmel W Choi Janine Cerutti Yiwen Zhunull nullErin C Dunn

Published in: Journal of child psychology and psychiatry, and allied disciplines (2020)

This study highlights differences in polygenic loading for depressive symptoms across childhood and adolescence, particularly among youths with high symptoms in early adolescence, regardless of age-independent patterns.

Keyphrases

depressive symptoms
major depressive disorder
sleep quality
social support
bipolar disorder
early life
childhood cancer
gene expression
copy number