ICBP90 Regulates MIF Expression, Glucocorticoid Sensitivity, and Apoptosis at the MIF Immune Susceptibility Locus.

Jie YaoLin LengWeiling FuJia LiChristian BronnerRichard John Bucala

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2021)

These findings suggest a mechanism for genetic variation of glucocorticoid-regulated MIF transcription, with implications for autoimmune disease severity and glucocorticoid responsiveness.

Keyphrases

transcription factor
poor prognosis
oxidative stress
endoplasmic reticulum stress
cell cycle arrest