Postpartum relapses increase the risk of disability progression in multiple sclerosis: the role of disease modifying drugs.
Emilio PortaccioAngelo GhezziBahia HakikiAndrea SturchioVittorio MartinelliLucia MoiolaFrancesco PattiGian Luigi MancardiClaudio SolaroMaria Rosaria TolaCarlo PozzilliLaura De GiglioRocco TotaroAlessandra LugaresiGiovanna De LucaDamiano PaolicelliMaria Giovanna MarrosuGiancarlo ComiMaria TrojanoMaria Pia Amatonull nullPublished in: Journal of neurology, neurosurgery, and psychiatry (2014)
Our findings show an increased risk of postpartum relapses and disability accrual in women with higher disease activity before and during pregnancy. Since it may reduce the risk of postpartum relapses, early DMD resumption should be encouraged, particularly in patients with more active disease.