Polygenic scores for longitudinal prediction of incident type 2 diabetes in an ancestrally and medically diverse primary care physician network: a patient cohort study.
Ravi MandlaPhilip SchroederBianca PornealaJose C FlorezJames B MeigsJosep M MercaderAaron LeongPublished in: Genome medicine (2024)
Genetic information can help identify high-risk patients even among those perceived to be low risk in a clinical evaluation.
Keyphrases
- primary care
- type diabetes
- clinical evaluation
- end stage renal disease
- ejection fraction
- cardiovascular disease
- newly diagnosed
- emergency department
- chronic kidney disease
- mental health
- depressive symptoms
- prognostic factors
- case report
- genome wide
- social support
- metabolic syndrome
- gene expression
- dna methylation
- general practice
- weight loss