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The Effect of Endothelin Receptor Antagonists in Patients with Eisenmenger Syndrome: A Systematic Review.

Abdelrahman ElshafayDuy Hieu TruongMohamed M AboElnasHossam IdreesHatem G MetwaliNguyen Lam VuongOmar Ahmed SaadKenji HirayamaNguyen Tien Huy
Published in: American journal of cardiovascular drugs : drugs, devices, and other interventions (2018)
This study demonstrated safety and improved hemodynamic effects of bosentan in ES, with a controversial effect on exercise capacity. Further randomized controlled trials with longer follow-up duration are needed to confirm these results.
Keyphrases
  • randomized controlled trial
  • high intensity
  • pulmonary arterial hypertension
  • physical activity
  • clinical trial
  • pulmonary hypertension