Unchecked autoreactive CD8 + T cells wreak havoc in cancer immunotherapy.

Published in: Nature cardiovascular research (2022)

Cytotoxic T cells react to cardiac peptides in patients with cancer that receive immunotherapy, resulting in myocarditis. Identifying the targets for T cells in patients who are immunosuppressed will enable a better understanding of individual risk before treatment is initiated.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
left ventricular
prognostic factors
heart failure
patient reported outcomes
smoking cessation