Slava Epelman

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 34

Top Venues

Cell death and differentiation

Nature metabolism

Circulation research

Nature cardiovascular research

University of Toronto

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Toronto

Canada

Assistant Professor :: Immunology, Laboratory Medicine and Pathobiology

University Health Network

Canada

Staff Cardiologist :: Department of Medicine

University Health Network

Canada

Clinician Scientist :: Cardiology

Mount Sinai Hospital

Canada

Associate Staff :: Cardiology

Publications

Megan Holt, Julia Lin, Markus Cicka, Anthony Wong, Slava Epelman, Kory J Lavine
Dissecting and Visualizing the Functional Diversity of Cardiac Macrophages. Circulation research 134 (12) (2024)
Robert Nechanitzky, Parameswaran Ramachandran, Duygu Nechanitzky, Wanda Y Li, Andrew C Wakeham, Jillian Haight, Mary E Saunders, Slava Epelman, Tak Wah Mak
CaSSiDI: novel single-cell "Cluster Similarity Scoring and Distinction Index" reveals critical functions for PirB and context-dependent Cebpb repression. Cell death and differentiation 31 (3) (2024)
Megan Holt, Julia Lin, Markus Cicka, Anthony Wong, Slava Epelman, Kory J Lavine
Dissecting and Visualizing the Functional Diversity of Cardiac Macrophages. Circulation research 134 (12) (2024)
Robert Nechanitzky, Parameswaran Ramachandran, Duygu Nechanitzky, Wanda Y Li, Andrew C Wakeham, Jillian Haight, Mary E Saunders, Slava Epelman, Tak Wah Mak
CaSSiDI: novel single-cell "Cluster Similarity Scoring and Distinction Index" reveals critical functions for PirB and context-dependent Cebpb repression. Cell death and differentiation (2024)
Xiangyu Zhang, Divya Kapoor, Se-Jin Jeong, Alan Fappi, Jeremiah Stitham, Vasavi Shabrish, Ismail Sergin, Eman Yousif, Astrid Rodriguez-Velez, Yu-Sheng Yeh, Arick C Park, Arif Yurdagul, Oren Rom, Slava Epelman, Joel D Schilling, Marco Sardiello, Abhinav Diwan, Jaehyung Cho, Nathan O Stitziel, Ali Javaheri, Irfan J Lodhi, Bettina Mittendorfer, Babak Razani
Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk. Nature metabolism 6 (2) (2024)
Robert Nechanitzky, Parameswaran Ramachandran, Duygu Nechanitzky, Wanda Y Li, Andrew C Wakeham, Jillian Haight, Mary E Saunders, Slava Epelman, Tak Wah Mak
CaSSiDI: novel single-cell "Cluster Similarity Scoring and Distinction Index" reveals critical functions for PirB and context-dependent Cebpb repression. Cell death and differentiation 31 (3) (2024)
Xiangyu Zhang, Divya Kapoor, Se-Jin Jeong, Alan Fappi, Jeremiah Stitham, Vasavi Shabrish, Ismail Sergin, Eman Yousif, Astrid Rodriguez-Velez, Yu-Sheng Yeh, Arick C Park, Arif Yurdagul, Oren Rom, Slava Epelman, Joel D Schilling, Marco Sardiello, Abhinav Diwan, Jaehyung Cho, Nathan O Stitziel, Ali Javaheri, Irfan J Lodhi, Bettina Mittendorfer, Babak Razani
Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk. Nature metabolism 6 (2) (2024)
Robert Nechanitzky, Parameswaran Ramachandran, Duygu Nechanitzky, Wanda Y Li, Andrew C Wakeham, Jillian Haight, Mary E Saunders, Slava Epelman, Tak Wah Mak
CaSSiDI: novel single-cell "Cluster Similarity Scoring and Distinction Index" reveals critical functions for PirB and context-dependent Cebpb repression. Cell death and differentiation 31 (3) (2024)
Robert Nechanitzky, Parameswaran Ramachandran, Duygu Nechanitzky, Wanda Y Li, Andrew C Wakeham, Jillian Haight, Mary E Saunders, Slava Epelman, Tak Wah Mak
CaSSiDI: novel single-cell "Cluster Similarity Scoring and Distinction Index" reveals critical functions for PirB and context-dependent Cebpb repression. Cell death and differentiation 31 (3) (2024)
Xiangyu Zhang, Divya Kapoor, Se-Jin Jeong, Alan Fappi, Jeremiah Stitham, Vasavi Shabrish, Ismail Sergin, Eman Yousif, Astrid Rodriguez-Velez, Yu-Sheng Yeh, Arick C Park, Arif Yurdagul, Oren Rom, Slava Epelman, Joel D Schilling, Marco Sardiello, Abhinav Diwan, Jaehyung Cho, Nathan O Stitziel, Ali Javaheri, Irfan J Lodhi, Bettina Mittendorfer, Babak Razani
Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk. Nature metabolism 6 (2) (2024)
Xiangyu Zhang, Divya Kapoor, Se-Jin Jeong, Alan Fappi, Jeremiah Stitham, Vasavi Shabrish, Ismail Sergin, Eman Yousif, Astrid Rodriguez-Velez, Yu-Sheng Yeh, Arick C Park, Arif Yurdagul, Oren Rom, Slava Epelman, Joel D Schilling, Marco Sardiello, Abhinav Diwan, Jaehyung Cho, Nathan O Stitziel, Ali Javaheri, Irfan J Lodhi, Bettina Mittendorfer, Babak Razani
Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk. Nature metabolism 6 (2) (2024)
Robert Nechanitzky, Parameswaran Ramachandran, Duygu Nechanitzky, Wanda Y Li, Andrew C Wakeham, Jillian Haight, Mary E Saunders, Slava Epelman, Tak Wah Mak
CaSSiDI: novel single-cell "Cluster Similarity Scoring and Distinction Index" reveals critical functions for PirB and context-dependent Cebpb repression. Cell death and differentiation 31 (3) (2024)
Robert Nechanitzky, Parameswaran Ramachandran, Duygu Nechanitzky, Wanda Y Li, Andrew C Wakeham, Jillian Haight, Mary E Saunders, Slava Epelman, Tak Wah Mak
CaSSiDI: novel single-cell "Cluster Similarity Scoring and Distinction Index" reveals critical functions for PirB and context-dependent Cebpb repression. Cell death and differentiation 31 (3) (2024)
Xiangyu Zhang, Divya Kapoor, Se-Jin Jeong, Alan Fappi, Jeremiah Stitham, Vasavi Shabrish, Ismail Sergin, Eman Yousif, Astrid Rodriguez-Velez, Yu-Sheng Yeh, Arick C Park, Arif Yurdagul, Oren Rom, Slava Epelman, Joel D Schilling, Marco Sardiello, Abhinav Diwan, Jaehyung Cho, Nathan O Stitziel, Ali Javaheri, Irfan J Lodhi, Bettina Mittendorfer, Babak Razani
Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk. Nature metabolism 6 (2) (2024)
Xiangyu Zhang, Divya Kapoor, Se-Jin Jeong, Alan Fappi, Jeremiah Stitham, Vasavi Shabrish, Ismail Sergin, Eman Yousif, Astrid Rodriguez-Velez, Yu-Sheng Yeh, Arick C Park, Arif Yurdagul, Oren Rom, Slava Epelman, Joel D Schilling, Marco Sardiello, Abhinav Diwan, Jaehyung Cho, Nathan O Stitziel, Ali Javaheri, Irfan J Lodhi, Bettina Mittendorfer, Babak Razani
Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk. Nature metabolism 6 (2) (2024)
Qiuyun Pan, Ping Yan, Alexander Byungsuk Kim, Qingli Xiao, Gaurav Pandey, Hans Haecker, Slava Epelman, Abhinav Diwan, Jin-Moo Lee, Carl J DeSelm
Chimeric Antigen Receptor Macrophages Target and Resorb Amyloid Plaques in a Mouse Model of Alzheimer's Disease. bioRxiv : the preprint server for biology (2023)
Xiangyu Zhang, Trent D Evans, Sunny Chen, Ismail Sergin, Jeremiah Stitham, Se-Jin Jeong, Astrid Rodriguez-Velez, Yu-Sheng Yeh, Arick C Park, In-Hyuk Jung, Abhinav Diwan, Joel D Schilling, Oren Rom, Arif Yurdagul, Slava Epelman, Jaehyung Cho, Irfan J Lodhi, Bettina Mittendorfer, Babak Razani
Loss of Macrophage mTORC2 Drives Atherosclerosis via FoxO1 and IL-1β Signaling. Circulation research (2023)
Pailin Chiaranunt, Kyle Burrows, Louis Ngai, Siu Ling Tai, Eric Yixiao Cao, Helen Liang, Homaira Hamidzada, Anthony Wong, Julia Gschwend, Pascal Flüchter, Meggie Kuypers, Tijana Despot, Abdul Momen, Sung Min Lim, Thierry Mallevaey, Christoph Schneider, Tyrrell Conway, Hiromi Imamura, Slava Epelman, Arthur Mortha
Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling. Science immunology 8 (86) (2023)
Qiuyun Pan, Ping Yan, Alexander Byungsuk Kim, Qingli Xiao, Gaurav Pandey, Hans Haecker, Slava Epelman, Abhinav Diwan, Jin-Moo Lee, Carl J DeSelm
Chimeric Antigen Receptor Macrophages Target and Resorb Amyloid Plaques in a Mouse Model of Alzheimer's Disease. bioRxiv : the preprint server for biology (2023)
Ian Fernandes, Shunsuke Funakoshi, Homaira Hamidzada, Slava Epelman, Gordon M Keller
Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cells. Nature communications 14 (1) (2023)
Qiuyun Pan, Ping Yan, Alexander Byungsuk Kim, Qingli Xiao, Gaurav Pandey, Hans Haecker, Slava Epelman, Abhinav Diwan, Jin-Moo Lee, Carl J DeSelm
Chimeric Antigen Receptor Macrophages Target and Resorb Amyloid Plaques in a Mouse Model of Alzheimer's Disease. bioRxiv : the preprint server for biology (2023)
Sarah A Dick, Anthony Wong, Homaira Hamidzada, Sara Nejat, Robert Nechanitzky, Shabana Vohra, Brigitte Mueller, Rysa Zaman, Crystal Kantores, Laura Aronoff, Abdul Momen, Duygu Nechanitzky, Wanda Y Li, Parameswaran Ramachandran, Sarah Q Crome, Burkhard Becher, Myron I Cybulsky, Filio Billia, Shaf Keshavjee, Seema Mital, Clint S Robbins, Tak Wah Mak, Slava Epelman
Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles. Science immunology 7 (67) (2022)
Anthony Wong, Slava Epelman
Unchecked autoreactive CD8 + T cells wreak havoc in cancer immunotherapy. Nature cardiovascular research 1 (12) (2022)
Homaira Hamidzada, Slava Epelman
Rel-driven monocyte-derived macrophages push the pressured heart over the edge. Cardiovascular research 118 (5) (2022)
Augustin Toma, Claudia C Dos Santos, Beata Burzynska, Monika Góra, Marek Kiliszek, Natalie Stickle, Holger Kirsten, Leah B Kosyakovsky, Bo Wang, Sean Van Diepen, Slava Epelman, Yishay Szekely, John C Marshall, Filio Billia, Patrick R Lawler
Diversity in the Expressed Genomic Host Response to Myocardial Infarction. Circulation research 131 (1) (2022)
Anthony Wong, Slava Epelman
Unchecked autoreactive CD8 + T cells wreak havoc in cancer immunotherapy. Nature cardiovascular research 1 (12) (2022)
Anthony Wong, Slava Epelman
Unchecked autoreactive CD8 + T cells wreak havoc in cancer immunotherapy. Nature cardiovascular research 1 (12) (2022)
Laura M Snell, Wenxi Xu, Diala Abd-Rabbo, Giselle Boukhaled, Mengdi Guo, Bethany L Macleod, Heidi J Elsaesser, Kebria Hezaveh, Nirmin Alsahafi, Sabelo Lukhele, Sara Nejat, Ramanandan Prabhakaran, Slava Epelman, Tracy L McGaha, David G Brooks
Dynamic CD4+ T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection. Nature immunology 22 (12) (2021)
Anthony Wong, Slava Epelman
Tissue-Reparative Benefits of MST1/2 Inhibition: Separating the Wheat From the Chaff. Circulation research 129 (10) (2021)
Ming Wang, Yalong Yang, Dilay Cansever, Yiming Wang, Crystal Kantores, Sébastien Messiaen, Delphine Moison, Gabriel Livera, Svetoslav Chakarov, Tobias Weinberger, Christopher Stremmel, Monika Fijak, Britta Klein, Christiane Pleuger, Zhexiong Lian, Wentao Ma, Qingzhi Liu, Kathrin Klee, Kristian Händler, Thomas Ulas, Andreas Schlitzer, Joachim L Schultze, Burkhard Becher, Melanie Greter, Zhaoyuan Liu, Florent Ginhoux, Slava Epelman, Christian Schulz, Andreas Meinhardt, Sudhanshu Bhushan
Two populations of self-maintaining monocyte-independent macrophages exist in adult epididymis and testis. Proceedings of the National Academy of Sciences of the United States of America 118 (1) (2021)
Jesse W Williams, Konstantin Zaitsev, Ki-Wook Kim, Stoyan Ivanov, Brian T Saunders, Patricia R Schrank, Kyeongdae Kim, Andrew Elvington, Seung Hyeon Kim, Christopher G Tucker, Mary Wohltmann, Justin A Spanier, Slava Epelman, Maxim N Artyomov, Kory J Lavine, Bernd H Zinselmeyer, Jae-Hoon Choi, Gwendalyn J Randolph
Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression. Nature immunology 21 (10) (2020)
Xiangyu Zhang, Ismail Sergin, Trent D Evans, Se-Jin Jeong, Astrid Rodriguez-Velez, Divya Kapoor, Sunny Chen, Eric Song, Karyn B Holloway, Jan R Crowley, Slava Epelman, Conrad C Weihl, Abhinav Diwan, Daping Fan, Bettina Mittendorfer, Nathan O Stitziel, Joel D Schilling, Irfan J Lodhi, Babak Razani
High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy. Nature metabolism 2 (1) (2020)
Sheojung Shin, Peter C Austin, Heather Joan Ross, Husam Abdel-Qadir, Cassandra Freitas, George Tomlinson, Davide Chicco, Meera Mahendiran, Patrick R Lawler, Filio Billia, Anthony O Gramolini, Slava Epelman, Bo Wang, Douglas S Lee
Machine learning vs. conventional statistical models for predicting heart failure readmission and mortality. ESC heart failure 8 (1) (2020)
Sarah A Dick, Jillian A Macklin, Sara Nejat, Abdul Momen, Xavier Clemente-Casares, Marwan G Althagafi, Jinmiao Chen, Crystal Kantores, Siyavash Hosseinzadeh, Laura Aronoff, Anthony Wong, Rysa Zaman, Iulia Barbu, Rickvinder Besla, Kory J Lavine, Babak Razani, Florent Ginhoux, Mansoor Husain, Myron I Cybulsky, Clinton S Robbins, Slava Epelman
Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction. Nature immunology 20 (1) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Slava Epelman