Clinical Outcomes Associated With Methylprednisolone in Mechanically Ventilated Patients With COVID-19.

Brian C NelsonJustin LaracySherif ShoucriDonald DietzJason E ZuckerNina PatelMagdalena E SobieszczykChristine J KubinAngela Gomez-Simmonds

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)

Methylprednisolone was associated with increased ventilator-free days and higher probability of extubation in a propensity-score matched cohort. Randomized, controlled studies are needed to further define methylprednisolone use in patients with COVID-19.

Keyphrases

high dose
acute respiratory distress syndrome
mechanical ventilation
intensive care unit
double blind
open label
cardiac surgery
low dose
placebo controlled
extracorporeal membrane oxygenation
randomized controlled trial
acute kidney injury
respiratory failure
study protocol