Pilot study of a ketogenic diet in bipolar disorder.
Nicole NeedhamIain H CampbellHelen GrossiIvana KamenskaBenjamin P RigbySharon A SimpsonEmma McIntoshPankaj BahugunaBen MeadowcroftFrances CreasyMaja Mitchell-GrigorjevaJohn NorrieGerard ThompsonMelissa C GibbsAilsa McLellanCheryl FisherTessa MosesKarl BurgessRachel BrownMichael J ThrippletonHarry CampbellDaniel J SmithPublished in: BJPsych open (2023)
The recruitment and retention of euthymic individuals with bipolar disorder to a 6-8 week ketogenic diet intervention was feasible, with high completion rates for outcome measures. The majority of participants reached and maintained ketosis, and adverse events were generally mild and modifiable. A future randomised controlled trial is now warranted.