Oxytocin Receptors on Calvarial Periosteal Innervation: Therapeutic Target for Post-Traumatic Headache?

Vimala N BharadwajMichael KlukinovRobert Paul CowanNazanin MahinparvarDavid John ClarkDavid Clifford Yeomans

Published in: Pharmaceutics (2024)

Taken together, our observations suggest that periosteal trigeminal afferents contribute to post-TBI craniofacial pain, and that periosteum tissue can be used as a potential local target for therapeutics such as oxytocin.

Keyphrases

neuropathic pain
traumatic brain injury
chronic pain
pain management
small molecule
spinal cord
severe traumatic brain injury
spinal cord injury
human health
bone regeneration
mild traumatic brain injury
risk assessment