Added value of chromosomal microarray analysis over conventional karyotyping in stillbirth work-up: systematic review and meta-analysis.

Raigam Jafet Martínez-Portilla Montse PautaA Hawkins-VillarrealM Rial-CresteloF Paz Y MiñoI MadrigalF FiguerasAntoni Borrell

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2019)

CMA, incorporated into the stillbirth work-up, improves both the test success rate and the detection of genetic anomalies compared with conventional karyotyping. To achieve a genetic diagnosis in stillbirth is particularly relevant for the purpose of counseling regarding future pregnancies. Copyright © 2018 ISUOG. Published by John Wiley & Sons Ltd.

Keyphrases

copy number
genome wide
preterm birth
randomized controlled trial
label free
systematic review
pregnant women
real time pcr
hiv testing
human immunodeficiency virus
pregnancy outcomes
men who have sex with men
hiv infected