Magnetic Hyperthermia as an adjuvant cancer therapy in combination with radiotherapy versus radiotherapy alone for recurrent/progressive glioblastoma: a systematic review.
Sakine ShirvalilouSamideh KhoeiAzam Janati EsfahaniMahboobeh KamaliMilad ShirvalilooRoghayeh SheervalilouParvin MirzaghavamiPublished in: Journal of neuro-oncology (2021)
Our systematic review indicates that MH therapy as an adjuvant for RT could result in improved survival, compared to the therapeutic outcomes achieved with RT alone in GBM, especially by intratumoral injection of magnetic nanoparticles. However, heterogeneity in the methodology of the most well-known studies, and differences in the study design may significantly limit the extent to which conclusions can be drawn. Thus, further investigations are required to shed more light on the efficacy of MH therapy as an adjuvant treatment modality in GBM.
Keyphrases
- early stage
- systematic review
- magnetic nanoparticles
- cancer therapy
- radiation therapy
- multiple sclerosis
- meta analyses
- locally advanced
- radiation induced
- drug delivery
- squamous cell carcinoma
- randomized controlled trial
- type diabetes
- rectal cancer
- stem cells
- metabolic syndrome
- mass spectrometry
- mesenchymal stem cells
- cell therapy
- free survival
- case control
- smoking cessation